Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p382 | Osteoporosis: treatment | ECTS2016

Effects of single bolus injection of vitamin D on serum FGF23, Sclerostin and DKK1 concentrations in vitamin D-deficient subjects

Dong Jang Dong , Choi Hoon , Lim Sung-Kil

Objective: Bone is one of endocrine organ and osteocytes secretes FGF23, Sclerostin and DKK1. FGF23 inhibits renal phosphate reabsorption and suppresses 1-α hydroxylase activity. Calcitriol stimulates FGF23 synthesis in bone. We aimed to determine the effect of single bolus injection of vitamin D on serum FGF23, DKK1 and Sclerostin concentrations in vitamin D-deficient subjects.Design and methods: The study group was composed of placebo group with s...